Joelinton replaces Dwight Gayle up front as Newcastle take on Manchester United at Old Trafford and try to distance themselves from the Premier League’s bottom three.
That’s the only change head coach Steve Bruce makes to the side beaten 2-0 by Chelsea six days ago, with Gayle joining fellow striker Andy Carroll on the bench.
Karl Darlow continues in goal, with Emil Krafth, Jamaal Lascelles, Ciaran Clark and Jamal Lewis making up the backline right to left.
It remains to be seen whether Isaac Hayden drops back to join Lascelles and Clark, with two other central midfielders, Jonjo Shelvey and Joe Willock, also starting.
Elsewhere, Miguel Almirón and Allan Saint-Maximin will look to support Joelinton at the top end of the pitch.
Ryan Fraser and Jacob Murphy are among Bruce’s other attack-minded reinforcements on the bench.
Newcastle United: Karl Darlow, Emil Krafth, Jamaal Lascelles, Ciaran Clark, Jamal Lewis, Isaac Hayden, Jonjo Shelvey, Joe Willock, Miguel Almirón, Allan Saint-Maximin, Joelinton.
Substitutes: Martin Dúbravka, Paul Dummett, Jacob Murphy, Matt Ritchie, Jeff Hendrick, Sean Longstaff, Ryan Fraser, Andy Carroll, Dwight Gayle.