Alan Pardew's reign as Newcastle manager got off to the perfect start as United's own Merseyside contingent put Liverpool to the sword in front of a packed St. James' Park.
Boyhood Reds fan Kevin Nolan
and Evertonian Joey Barton
were instrumental in the victory, grabbing a goal each before Andy Carroll
's injury-time strike handed Pardew victory in his first game in charge.
Despite dominating for periods either side of half-time, Roy Hodgson's side ended the game well beaten and the result saw Newcastle move above Liverpool in the Premier League table.
It was a move straight from the training ground that saw the Magpies
snatch the lead after quarter-of-an-hour, and when Barton's flighted free-kick was met by the head of Carroll, the knock-down fell to Nolan, who prodded home from close-range.
Despite a sustained bout of pressure from the visitors, United carried their lead into half-time but the Reds were level just four minutes after the restart when a defensive mix-up allowed Dirk Kuyt to steer home a deflected equaliser.
The goal looked to have galvanised Liverpool, but their momentum came to nothing, and it was Newcastle who grew in confidence as the game entered the final 20 minutes.
Nile Ranger's introduction from the bench caused Hodgson's defence all sorts of problems and he was instrumental in giving United the lead, flicking Tim Krul
's long kick into the path of Barton, who put the loose ball beyond Reina.
Having looked static for United's second, Liverpool's back-line were at sixes and sevens again in stoppage time as they stood off and allowed Andy Carroll
to smash home a lethal shot from 25-yards.