The Journal's Great North Fitness Revolution campaign will be launched at St. James' Park on Sunday during the half-time interval of United's match with West Bromwich Albion
The Great North Fitness Revolution aims to improve the health and wellbeing of the people in the region.
The North East is the second most obese area in Europe and the aim is to get as many people as possible to sign up and join the revolution.
The campaign will encourage as many people as possible to make even small improvements to what they eat and drink and what they do for exercise. The more people who make a small change then the bigger the difference this will make to the obesity levels in the North East.
The Journal and the Great North Run are spearheading the revolution - two iconic North East brands joining forces to make that difference.
The call to action will be made to individuals, couples, families, groups of friends, workmates, clubs, organisations, schools, shops, offices, factories - even whole villages.
There is a whole host of challenges for people to sign up to covering food and drink, walking, cycling, swimming, running and aerobic exercise (gym and dance).
The campaign will last for 18 months through to the 2012 Great North Run.
Newcastle United captain Kevin Nolan said: "This is a fantastic campaign and I encourage as many people as possible in the region to sign up to it. In today's society personal wellbeing is very important - living a healthy lifestyle can bring a whole new spring in your step."
And defender Steven Taylor added: "Keeping fit is great fun and eating sensibly is the key to getting your body in the shape you want it to be. Sign up and be part of the revolution."