By Dan King
Jose Enrique believes one more win will ensure United's Barclays Premier League safety despite Sunday's 1-0 defeat to Aston Villa - a game where the Spaniard made a successful return following a hamstring injury.
And he has urged his Magpies team-mates to take advantage of their next opponents' hectic schedule to get that victory against Manchester United in Newcastle's next game.
The Red Devils face Chelsea on Tuesday in the quarter-finals of the Champions League, before meeting local rivals Manchester City next weekend for a place in the FA Cup final. Newcastle, meanwhile, now have nine days to rest and train before they host the league leaders.
"I think we need one more win and we will stay up," said the full-back, who spoke exclusively to nufc.co.uk after the Villa defeat. "The next game is against Manchester United and they're a very good team.
"It will be difficult to beat them but we have to have the attitude that anything can happen.
"They have two games next week so we will have a longer rest. That's good for us, so we'll try and beat them."
Enrique also reflected on the match at Villa Park, where James Collins' goal proved the difference between the the two sides.
It was the Valencia-born defender's first full game since February, after he missed the 4-1 win over Wolves and limped off against both Everton and Stoke in March.
He said: "I'm happy to have played, because it was hard to have to sit out of the Wolves game, especially with that coming two weeks after the Stoke match. So it felt like a long time and I'm grateful to the physios for working hard with me to come back.
"But of course, it was disappointing that the team lost today. It is never good to lose and now we have to think about the next game.
"I think the game changed when they scored a goal. They scored at a good time for them. But we still had chances. Peter (Lovenkrands) had two, Nile (Ranger) had one too.
"We had opportunities and when you have opportunities you have to take them."